High clearance definition
WebQuestion: A new drug for hypertension has high intrinsic clearance in healthy volunteers (1400 L/h). When tested in a patient with reduced liver function (alcoholic cirrhosis), the … Web21 de nov. de 2024 · Hepatic clearance. The two major determinants of hepatic clearance are the efficiency of drug removal from the blood and the efficiency of blood delivery to the liver. The former is described by the hepatic extraction ratio, and the latter is simply the blood flow to the liver. Thus, the equation below is basically "flow times extraction ratio ...
High clearance definition
Did you know?
Webclear•ance (klēr′ əns), n. the act of clearing. the distance between two objects; an amount of clear space: The bridge allowed a clearance of 37 feet at mean high water. a formal …
In pharmacology, clearance is a pharmacokinetic measurement of the volume of plasma from which a substance is completely removed per unit time. Usually, clearance is measured in L/h or mL/min. The quantity reflects the rate of drug elimination divided by plasma concentration. Excretion, on the other hand, is a measurement of the amount of a substance removed from the body per unit time (e.g., mg/min, μg/min, etc.). While clearance and excretion of a substance ar… Webclearance - WordReference English dictionary, questions, discussion and forums. All Free. WordReference.com Online Language Dictionaries. ... The bridge allowed a clearance of 37 feet at mean high water. a formal authorization permitting access to classified information, documents, etc.
WebClearance (civil engineering) In civil engineering , clearance refers to the difference between the loading gauge and the structure gauge in the case of railroad cars or trams , … WebRenal clearance (CL R) is the net result of glomerular filtration of unbound drug plus tubular secretion minus tubular reabsorption. An acute or chronic reduction in GFR results in a …
WebThe definition of clearance Clearance describes the relationship between concentration and the rate of elimination of drug from the body TUTORIAL. Vol. 23, No.2, Dec 15, 2015 43 TCP Transl Clin Pharmacol Rate Out = CL • Concentration Because the definition of clearance is linked directly to concen-
WebExamples of high clearance in a sentence, how to use it. 15 examples: The starting dose of high clearance drugs should therefore be reduced by… lithonia wpx1 led p2 40k mvolt ddbxdWeb2. : the distance by which one object clears another or the clear space between them. 3. : the volume of blood or plasma that can be freed of a specified constituent in a … lithonia wpx2 led 40k mvoltWebYou can go to the definition of high or the definition of clearance. Or, see other combinations with clearance . These examples are from corpora and from sources on the web. lithonia wpx1 led p2 40k mvolt dwhxdWebHigh Clearance Vehicle. Generally a truck, pickup truck, SUV or ATV with a road clearance that allows travel on low standard roads without vehicle damage and greater than the … lithonia wpx3 ledhttp://panonclearance.com/your-value-vs-reference-range lithonia wraparound lens coverWebclearance noun [U] (NOT TOUCH) the amount of space available for an object to pass through an opening without touching anything, or for two objects to pass each other … lithonia wraparoundWebSave. High clearance means you need a vehicle that is "high off the ground" like 4X4s. The measurement is from the ground to the lowest part of the vehicle, like axels or oil … lithonia wpx3